Pharmacist salary in Sioux Falls, SD-MN

Pharmacists in the Sioux Falls, SD-MN metro area earn a median of $148,330 a year ($71.31 an hour), based on BLS data for 690 workers.

Median salary
$148,330
Hourly
$71.31
Average
$145,350
Top 10% earn
$174,070
Workers
690

Pay ranges from $123,700 for the lowest-paid 10% to $174,070 for the top 10%. That is 5% higher than the national median of $140,910. Pay here is 1% higher than the South Dakota statewide median of $146,790. There are 3.8 pharmacists per 1,000 jobs here — the job is 1.9× more common than nationally. The average (mean) salary is $145,350, close to the median.

Pay range for pharmacists in Sioux Falls, SD-MN

$0$190,000
Pay levelYearlyHourly
10th percentile (entry level)$123,700$59.47
25th percentile$135,680$65.23
Median$148,330$71.31
75th percentile$162,770$78.26
90th percentile (top earners)$174,070$83.69
Average (mean)$145,350$69.88

Half of pharmacists earn more than the median and half earn less. Percentiles show the spread: 10% earn less than the 10th percentile, and 10% earn more than the 90th.

Median paycheck, before taxes

Pay periodAmount
Monthly$12,360.83
Semi-monthly (24 a year)$6,180.42
Biweekly (26 a year)$5,705
Weekly$2,852.50
Hourly$71.31

Based on a full-time year of 2,080 hours. Convert any amount with the hourly to salary converter.

Pharmacist salary in other metro areas nearby

Metro areaMedian salaryWorkers
Rochester, MN$164,250440
Minneapolis-St. Paul-Bloomington, MN-WI$160,9904,160
La Crosse-Onalaska, WI-MN$159,020210
Mankato, MN$157,010100
Duluth, MN-WI$154,860330
St. Cloud, MN$147,530230
Fargo, ND-MN$142,040520
Rapid City, SD$140,340210
Sioux City, IA-NE-SD$139,600120
Grand Forks, ND-MN$138,31090

Highest-paying states for pharmacists

StateMedian salary
Alaska$167,310
Oregon$165,960
California$164,610
Hawaii$163,220
Washington$160,610
Minnesota$159,740
Colorado$156,030
District of Columbia$153,400
Delaware$152,880
Wisconsin$148,740

See Pharmacist pay in every state or the South Dakota statewide figures.

Related jobs in Sioux Falls, SD-MN

JobMedian salaryHourly
Registered Nurse$75,350$36.23
Nurse Practitioner$130,390$62.69
Physical Therapist$91,470$43.98
Physician Assistant$135,790$65.28
Respiratory Therapist$63,630$30.59
Family Medicine Physician$258,910$124.48
Occupational Therapist$84,660$40.70
Dental Hygienist$92,350$44.40
Nurse Anesthetist$243,560$117.10
Speech-Language Pathologist$68,920$33.13
Dentists, General$181,140$87.09
Anesthesiologist$239,200+$115.00+
Dietitians and Nutritionists$64,890$31.20
Chiropractor$75,780$36.44

More: Healthcare Practitioners and Technical Occupations · all salaries in Sioux Falls, SD-MN

Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025 estimates, occupation code 29-1051. Wages include base pay, tips, commissions and shift pay, but not overtime, bonuses or benefits, and exclude the self-employed.

Frequently asked questions

How much does a pharmacist make in Sioux Falls, SD-MN?

The median salary for pharmacists in the Sioux Falls, SD-MN metro area is $148,330 a year, or $71.31 an hour. Pay ranges from $123,700 for the lowest-paid 10% to $174,070 for the top 10%.

How much do the highest-paid pharmacists make in Sioux Falls, SD-MN?

The top 10% of pharmacists in the Sioux Falls, SD-MN metro area earn at least $174,070 a year. The top 25% earn $162,770 or more.

What is the starting pay for pharmacists in Sioux Falls, SD-MN?

Entry-level pay (the 10th percentile) is about $123,700 a year, and a quarter of pharmacists earn $135,680 or less.

How many pharmacists work in Sioux Falls, SD-MN?

About 690 pharmacists are employed in the Sioux Falls, SD-MN metro area, not counting the self-employed.