Pharmacist salary in South Dakota

Pharmacists in South Dakota earn a median of $146,790 a year ($70.57 an hour), based on BLS data for 1,280 workers.

Median salary
$146,790
Hourly
$70.57
Average
$142,330
Top 10% earn
$166,340
Workers
1,280

Pay ranges from $112,200 for the lowest-paid 10% to $166,340 for the top 10%. That is 4% higher than the national median of $140,910. South Dakota ranks 13th of 51 states for pharmacists pay. There are 2.8 pharmacists per 1,000 jobs here — the job is 1.4× more common than nationally. The average (mean) salary is $142,330, close to the median.

Pay range for pharmacists in South Dakota

$0$190,000
Pay levelYearlyHourly
10th percentile (entry level)$112,200$53.94
25th percentile$131,950$63.44
Median$146,790$70.57
75th percentile$155,260$74.65
90th percentile (top earners)$166,340$79.97
Average (mean)$142,330$68.43

Half of pharmacists earn more than the median and half earn less. Percentiles show the spread: 10% earn less than the 10th percentile, and 10% earn more than the 90th.

Median paycheck, before taxes

Pay periodAmount
Monthly$12,232.50
Semi-monthly (24 a year)$6,116.25
Biweekly (26 a year)$5,645.77
Weekly$2,822.88
Hourly$70.57

Based on a full-time year of 2,080 hours. Convert any amount with the hourly to salary converter.

Pharmacist salary in cities in South Dakota

Metro areaMedian salaryWorkers
Sioux Falls, SD-MN$148,330690
Rapid City, SD$140,340210
Sioux City, IA-NE-SD$139,600120

Highest-paying states for pharmacists

StateMedian salary
Alaska$167,310
Oregon$165,960
California$164,610
Hawaii$163,220
Washington$160,610
Minnesota$159,740
Colorado$156,030
District of Columbia$153,400
Delaware$152,880
Wisconsin$148,740

See Pharmacist pay in every state.

Related jobs in South Dakota

JobMedian salaryHourly
Registered Nurse$78,060$37.53
Physical Therapist$92,660$44.55
Nurse Practitioner$128,840$61.94
Physician Assistant$133,200$64.04
Dental Hygienist$92,210$44.33
Family Medicine Physician$239,970$115.37
Occupational Therapist$85,050$40.89
Respiratory Therapist$68,240$32.81
Speech-Language Pathologist$65,680$31.58
Nurse Anesthetist$263,930$126.89
Dentists, General$158,140$76.03
Veterinarian$88,650$42.62
Chiropractor$76,210$36.64
Anesthesiologist$239,200+$115.00+

More: Healthcare Practitioners and Technical Occupations · all salaries in South Dakota

Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025 estimates, occupation code 29-1051. Wages include base pay, tips, commissions and shift pay, but not overtime, bonuses or benefits, and exclude the self-employed.

Frequently asked questions

How much does a pharmacist make in South Dakota?

The median salary for pharmacists in South Dakota is $146,790 a year, or $70.57 an hour. Pay ranges from $112,200 for the lowest-paid 10% to $166,340 for the top 10%.

How much do the highest-paid pharmacists make in South Dakota?

The top 10% of pharmacists in South Dakota earn at least $166,340 a year. The top 25% earn $155,260 or more.

What is the starting pay for pharmacists in South Dakota?

Entry-level pay (the 10th percentile) is about $112,200 a year, and a quarter of pharmacists earn $131,950 or less.

How many pharmacists work in South Dakota?

About 1,280 pharmacists are employed in South Dakota, not counting the self-employed.