Registered Nurse salary in Sioux Falls, SD-MN
Registered Nurses in the Sioux Falls, SD-MN metro area earn a median of $75,350 a year ($36.23 an hour), based on BLS data for 7,680 workers.
Pay ranges from $54,040 for the lowest-paid 10% to $97,330 for the top 10%. That is 23% lower than the national median of $97,550. Pay here is 3% lower than the South Dakota statewide median of $78,060. There are 43 registered nurses per 1,000 jobs here — the job is 2.0× more common than nationally. The average (mean) salary is $74,700, close to the median.
Pay range for registered nurses in Sioux Falls, SD-MN
| Pay level | Yearly | Hourly |
|---|---|---|
| 10th percentile (entry level) | $54,040 | $25.98 |
| 25th percentile | $65,070 | $31.29 |
| Median | $75,350 | $36.23 |
| 75th percentile | $81,690 | $39.28 |
| 90th percentile (top earners) | $97,330 | $46.79 |
| Average (mean) | $74,700 | $35.92 |
Half of registered nurses earn more than the median and half earn less. Percentiles show the spread: 10% earn less than the 10th percentile, and 10% earn more than the 90th.
Median paycheck, before taxes
| Pay period | Amount |
|---|---|
| Monthly | $6,279.17 |
| Semi-monthly (24 a year) | $3,139.58 |
| Biweekly (26 a year) | $2,898.08 |
| Weekly | $1,449.04 |
| Hourly | $36.23 |
Based on a full-time year of 2,080 hours. Convert any amount with the hourly to salary converter.
Registered Nurse salary in other metro areas nearby
| Metro area | Median salary | Workers |
|---|---|---|
| St. Cloud, MN | $105,290 | 2,910 |
| Mankato, MN | $103,400 | 1,570 |
| Minneapolis-St. Paul-Bloomington, MN-WI | $103,040 | 43,600 |
| Rochester, MN | $101,660 | 6,390 |
| La Crosse-Onalaska, WI-MN | $98,370 | 2,920 |
| Duluth, MN-WI | $96,940 | 4,410 |
| Fargo, ND-MN | $82,120 | 4,790 |
| Rapid City, SD | $79,380 | 2,480 |
| Grand Forks, ND-MN | $79,070 | 1,280 |
| Sioux City, IA-NE-SD | $75,840 | 1,600 |
Highest-paying states for registered nurses
| State | Median salary |
|---|---|
| California | $140,270 |
| Hawaii | $136,320 |
| Oregon | $129,010 |
| Washington | $124,200 |
| Alaska | $109,480 |
| New York | $109,440 |
| New Jersey | $106,500 |
| Massachusetts | $104,550 |
| Nevada | $103,670 |
| Connecticut | $102,740 |
See Registered Nurse pay in every state or the South Dakota statewide figures.
Related jobs in Sioux Falls, SD-MN
| Job | Median salary | Hourly |
|---|---|---|
| Pharmacist | $148,330 | $71.31 |
| Nurse Practitioner | $130,390 | $62.69 |
| Physical Therapist | $91,470 | $43.98 |
| Physician Assistant | $135,790 | $65.28 |
| Respiratory Therapist | $63,630 | $30.59 |
| Family Medicine Physician | $258,910 | $124.48 |
| Occupational Therapist | $84,660 | $40.70 |
| Dental Hygienist | $92,350 | $44.40 |
| Nurse Anesthetist | $243,560 | $117.10 |
| Speech-Language Pathologist | $68,920 | $33.13 |
| Dentists, General | $181,140 | $87.09 |
| Anesthesiologist | $239,200+ | $115.00+ |
| Dietitians and Nutritionists | $64,890 | $31.20 |
| Chiropractor | $75,780 | $36.44 |
More: Healthcare Practitioners and Technical Occupations · all salaries in Sioux Falls, SD-MN
Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025 estimates, occupation code 29-1141. Wages include base pay, tips, commissions and shift pay, but not overtime, bonuses or benefits, and exclude the self-employed.
Frequently asked questions
How much does a registered nurse make in Sioux Falls, SD-MN?
The median salary for registered nurses in the Sioux Falls, SD-MN metro area is $75,350 a year, or $36.23 an hour. Pay ranges from $54,040 for the lowest-paid 10% to $97,330 for the top 10%.
How much do the highest-paid registered nurses make in Sioux Falls, SD-MN?
The top 10% of registered nurses in the Sioux Falls, SD-MN metro area earn at least $97,330 a year. The top 25% earn $81,690 or more.
What is the starting pay for registered nurses in Sioux Falls, SD-MN?
Entry-level pay (the 10th percentile) is about $54,040 a year, and a quarter of registered nurses earn $65,070 or less.
How many registered nurses work in Sioux Falls, SD-MN?
About 7,680 registered nurses are employed in the Sioux Falls, SD-MN metro area, not counting the self-employed.