Nurse Practitioner salary in Sioux Falls, SD-MN

Nurse Practitioners in the Sioux Falls, SD-MN metro area earn a median of $130,390 a year ($62.69 an hour), based on BLS data for 500 workers.

Median salary
$130,390
Hourly
$62.69
Average
$127,620
Top 10% earn
$159,330
Workers
500

Pay ranges from $104,220 for the lowest-paid 10% to $159,330 for the top 10%. That is 1% lower than the national median of $132,300. Pay here is 1% higher than the South Dakota statewide median of $128,840. There are 2.8 nurse practitioners per 1,000 jobs here — the job is 1.4× more common than nationally. The average (mean) salary is $127,620, close to the median.

Pay range for nurse practitioners in Sioux Falls, SD-MN

$0$190,000
Pay levelYearlyHourly
10th percentile (entry level)$104,220$50.10
25th percentile$109,680$52.73
Median$130,390$62.69
75th percentile$137,600$66.15
90th percentile (top earners)$159,330$76.60
Average (mean)$127,620$61.35

Half of nurse practitioners earn more than the median and half earn less. Percentiles show the spread: 10% earn less than the 10th percentile, and 10% earn more than the 90th.

Median paycheck, before taxes

Pay periodAmount
Monthly$10,865.83
Semi-monthly (24 a year)$5,432.92
Biweekly (26 a year)$5,015
Weekly$2,507.50
Hourly$62.69

Based on a full-time year of 2,080 hours. Convert any amount with the hourly to salary converter.

Nurse Practitioner salary in other metro areas nearby

Metro areaMedian salaryWorkers
Mankato, MN$138,580150
Duluth, MN-WI$136,530420
Minneapolis-St. Paul-Bloomington, MN-WI$133,3704,900
St. Cloud, MN$131,520240
Grand Forks, ND-MN$130,990190
Fargo, ND-MN$130,070490
Sioux City, IA-NE-SD$129,060150
Rochester, MN$126,2701,190
La Crosse-Onalaska, WI-MN$125,390240
Rapid City, SD$124,160190

Highest-paying states for nurse practitioners

StateMedian salary
California$168,520
New Jersey$159,310
Washington$156,100
Oregon$155,680
Alaska$155,170
New York$153,510
Massachusetts$142,440
Nevada$140,670
Connecticut$138,470
New Hampshire$137,550

See Nurse Practitioner pay in every state or the South Dakota statewide figures.

Related jobs in Sioux Falls, SD-MN

JobMedian salaryHourly
Registered Nurse$75,350$36.23
Pharmacist$148,330$71.31
Physical Therapist$91,470$43.98
Physician Assistant$135,790$65.28
Respiratory Therapist$63,630$30.59
Family Medicine Physician$258,910$124.48
Occupational Therapist$84,660$40.70
Dental Hygienist$92,350$44.40
Nurse Anesthetist$243,560$117.10
Speech-Language Pathologist$68,920$33.13
Dentists, General$181,140$87.09
Anesthesiologist$239,200+$115.00+
Dietitians and Nutritionists$64,890$31.20
Chiropractor$75,780$36.44

More: Healthcare Practitioners and Technical Occupations · all salaries in Sioux Falls, SD-MN

Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025 estimates, occupation code 29-1171. Wages include base pay, tips, commissions and shift pay, but not overtime, bonuses or benefits, and exclude the self-employed.

Frequently asked questions

How much does a nurse practitioner make in Sioux Falls, SD-MN?

The median salary for nurse practitioners in the Sioux Falls, SD-MN metro area is $130,390 a year, or $62.69 an hour. Pay ranges from $104,220 for the lowest-paid 10% to $159,330 for the top 10%.

How much do the highest-paid nurse practitioners make in Sioux Falls, SD-MN?

The top 10% of nurse practitioners in the Sioux Falls, SD-MN metro area earn at least $159,330 a year. The top 25% earn $137,600 or more.

What is the starting pay for nurse practitioners in Sioux Falls, SD-MN?

Entry-level pay (the 10th percentile) is about $104,220 a year, and a quarter of nurse practitioners earn $109,680 or less.

How many nurse practitioners work in Sioux Falls, SD-MN?

About 500 nurse practitioners are employed in the Sioux Falls, SD-MN metro area, not counting the self-employed.