Physician Assistant salary in Sioux Falls, SD-MN
Physician Assistants in the Sioux Falls, SD-MN metro area earn a median of $135,790 a year ($65.28 an hour), based on BLS data for 290 workers.
Pay ranges from $106,660 for the lowest-paid 10% to $158,520 for the top 10%. That is about the same as the national median of $135,880. Pay here is 2% higher than the South Dakota statewide median of $133,200. There are 1.6 physician assistants per 1,000 jobs here — the job is 1.6× more common than nationally. The average (mean) salary is $132,350, close to the median.
Pay range for physician assistants in Sioux Falls, SD-MN
| Pay level | Yearly | Hourly |
|---|---|---|
| 10th percentile (entry level) | $106,660 | $51.28 |
| 25th percentile | $110,150 | $52.96 |
| Median | $135,790 | $65.28 |
| 75th percentile | $139,120 | $66.88 |
| 90th percentile (top earners) | $158,520 | $76.21 |
| Average (mean) | $132,350 | $63.63 |
Half of physician assistants earn more than the median and half earn less. Percentiles show the spread: 10% earn less than the 10th percentile, and 10% earn more than the 90th.
Median paycheck, before taxes
| Pay period | Amount |
|---|---|
| Monthly | $11,315.83 |
| Semi-monthly (24 a year) | $5,657.92 |
| Biweekly (26 a year) | $5,222.69 |
| Weekly | $2,611.35 |
| Hourly | $65.28 |
Based on a full-time year of 2,080 hours. Convert any amount with the hourly to salary converter.
Physician Assistant salary in other metro areas nearby
| Metro area | Median salary | Workers |
|---|---|---|
| Minneapolis-St. Paul-Bloomington, MN-WI | $145,030 | 2,340 |
| Mankato, MN | $142,020 | 70 |
| Rochester, MN | $137,340 | 480 |
| Fargo, ND-MN | $136,610 | 240 |
| Duluth, MN-WI | $135,860 | 200 |
| Grand Forks, ND-MN | $133,450 | 70 |
| St. Cloud, MN | $132,650 | 170 |
| Sioux City, IA-NE-SD | $130,970 | 70 |
| Rapid City, SD | $130,740 | 150 |
Highest-paying states for physician assistants
| State | Median salary |
|---|---|
| New Jersey | $165,690 |
| California | $165,650 |
| Washington | $164,360 |
| Hawaii | $164,050 |
| New York | $160,880 |
| Oregon | $155,780 |
| New Hampshire | $150,960 |
| Alaska | $150,700 |
| Vermont | $150,490 |
| Massachusetts | $142,410 |
See Physician Assistant pay in every state or the South Dakota statewide figures.
Related jobs in Sioux Falls, SD-MN
| Job | Median salary | Hourly |
|---|---|---|
| Registered Nurse | $75,350 | $36.23 |
| Pharmacist | $148,330 | $71.31 |
| Nurse Practitioner | $130,390 | $62.69 |
| Physical Therapist | $91,470 | $43.98 |
| Respiratory Therapist | $63,630 | $30.59 |
| Family Medicine Physician | $258,910 | $124.48 |
| Occupational Therapist | $84,660 | $40.70 |
| Dental Hygienist | $92,350 | $44.40 |
| Nurse Anesthetist | $243,560 | $117.10 |
| Speech-Language Pathologist | $68,920 | $33.13 |
| Dentists, General | $181,140 | $87.09 |
| Anesthesiologist | $239,200+ | $115.00+ |
| Dietitians and Nutritionists | $64,890 | $31.20 |
| Chiropractor | $75,780 | $36.44 |
More: Healthcare Practitioners and Technical Occupations · all salaries in Sioux Falls, SD-MN
Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025 estimates, occupation code 29-1071. Wages include base pay, tips, commissions and shift pay, but not overtime, bonuses or benefits, and exclude the self-employed.
Frequently asked questions
How much does a physician assistant make in Sioux Falls, SD-MN?
The median salary for physician assistants in the Sioux Falls, SD-MN metro area is $135,790 a year, or $65.28 an hour. Pay ranges from $106,660 for the lowest-paid 10% to $158,520 for the top 10%.
How much do the highest-paid physician assistants make in Sioux Falls, SD-MN?
The top 10% of physician assistants in the Sioux Falls, SD-MN metro area earn at least $158,520 a year. The top 25% earn $139,120 or more.
What is the starting pay for physician assistants in Sioux Falls, SD-MN?
Entry-level pay (the 10th percentile) is about $106,660 a year, and a quarter of physician assistants earn $110,150 or less.
How many physician assistants work in Sioux Falls, SD-MN?
About 290 physician assistants are employed in the Sioux Falls, SD-MN metro area, not counting the self-employed.