Nurse Practitioner salary in Missouri
Nurse Practitioners in Missouri earn a median of $129,930 a year ($62.47 an hour), based on BLS data for 7,710 workers.
Pay ranges from $100,650 for the lowest-paid 10% to $162,060 for the top 10%. That is 2% lower than the national median of $132,300. Missouri ranks 35th of 51 states for nurse practitioners pay. There are 2.6 nurse practitioners per 1,000 jobs here — the job is 1.3× more common than nationally. The average (mean) salary is $130,970, above the median because a few high earners pull it up.
Pay range for nurse practitioners in Missouri
| Pay level | Yearly | Hourly |
|---|---|---|
| 10th percentile (entry level) | $100,650 | $48.39 |
| 25th percentile | $119,910 | $57.65 |
| Median | $129,930 | $62.47 |
| 75th percentile | $144,640 | $69.54 |
| 90th percentile (top earners) | $162,060 | $77.91 |
| Average (mean) | $130,970 | $62.97 |
Half of nurse practitioners earn more than the median and half earn less. Percentiles show the spread: 10% earn less than the 10th percentile, and 10% earn more than the 90th.
Median paycheck, before taxes
| Pay period | Amount |
|---|---|
| Monthly | $10,827.50 |
| Semi-monthly (24 a year) | $5,413.75 |
| Biweekly (26 a year) | $4,997.31 |
| Weekly | $2,498.65 |
| Hourly | $62.47 |
Based on a full-time year of 2,080 hours. Convert any amount with the hourly to salary converter.
Nurse Practitioner salary in cities in Missouri
| Metro area | Median salary | Workers |
|---|---|---|
| St. Louis, MO-IL | $131,580 | 3,430 |
| Kansas City, MO-KS | $130,760 | 2,730 |
| Cape Girardeau, MO-IL | $130,000 | 200 |
| Columbia, MO | $128,930 | 330 |
| Jefferson City, MO | $128,710 | 130 |
| St. Joseph, MO-KS | $128,710 | 140 |
| Joplin, MO-KS | $126,640 | 230 |
| Springfield, MO | $125,630 | 660 |
Highest-paying states for nurse practitioners
| State | Median salary |
|---|---|
| California | $168,520 |
| New Jersey | $159,310 |
| Washington | $156,100 |
| Oregon | $155,680 |
| Alaska | $155,170 |
| New York | $153,510 |
| Massachusetts | $142,440 |
| Nevada | $140,670 |
| Connecticut | $138,470 |
| New Hampshire | $137,550 |
Related jobs in Missouri
| Job | Median salary | Hourly |
|---|---|---|
| Registered Nurse | $81,780 | $39.32 |
| Pharmacist | $137,610 | $66.16 |
| Physical Therapist | $99,310 | $47.75 |
| Physicians, All Other | $227,980 | $109.61 |
| Dental Hygienist | $92,750 | $44.59 |
| Family Medicine Physician | $171,180 | $82.30 |
| Occupational Therapist | $97,290 | $46.77 |
| Speech-Language Pathologist | $89,280 | $42.92 |
| Respiratory Therapist | $78,390 | $37.69 |
| Dentists, General | $204,960 | $98.54 |
| Physician Assistant | $135,130 | $64.96 |
| Veterinarian | $114,660 | $55.12 |
| Dietitians and Nutritionists | $65,450 | $31.47 |
| Nurse Anesthetist | $242,630 | $116.65 |
More: Healthcare Practitioners and Technical Occupations · all salaries in Missouri
Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025 estimates, occupation code 29-1171. Wages include base pay, tips, commissions and shift pay, but not overtime, bonuses or benefits, and exclude the self-employed.
Frequently asked questions
How much does a nurse practitioner make in Missouri?
The median salary for nurse practitioners in Missouri is $129,930 a year, or $62.47 an hour. Pay ranges from $100,650 for the lowest-paid 10% to $162,060 for the top 10%.
How much do the highest-paid nurse practitioners make in Missouri?
The top 10% of nurse practitioners in Missouri earn at least $162,060 a year. The top 25% earn $144,640 or more.
What is the starting pay for nurse practitioners in Missouri?
Entry-level pay (the 10th percentile) is about $100,650 a year, and a quarter of nurse practitioners earn $119,910 or less.
How many nurse practitioners work in Missouri?
About 7,710 nurse practitioners are employed in Missouri, not counting the self-employed.