Nurse Practitioner salary in St. Louis, MO-IL
Nurse Practitioners in the St. Louis, MO-IL metro area earn a median of $131,580 a year ($63.26 an hour), based on BLS data for 3,430 workers.
Pay ranges from $108,340 for the lowest-paid 10% to $164,280 for the top 10%. That is 1% lower than the national median of $132,300. Pay here is 1% higher than the Missouri statewide median of $129,930. There are 2.6 nurse practitioners per 1,000 jobs here — the job is 1.2× more common than nationally. The average (mean) salary is $135,550, above the median because a few high earners pull it up.
Pay range for nurse practitioners in St. Louis, MO-IL
| Pay level | Yearly | Hourly |
|---|---|---|
| 10th percentile (entry level) | $108,340 | $52.09 |
| 25th percentile | $127,460 | $61.28 |
| Median | $131,580 | $63.26 |
| 75th percentile | $154,500 | $74.28 |
| 90th percentile (top earners) | $164,280 | $78.98 |
| Average (mean) | $135,550 | $65.17 |
Half of nurse practitioners earn more than the median and half earn less. Percentiles show the spread: 10% earn less than the 10th percentile, and 10% earn more than the 90th.
Median paycheck, before taxes
| Pay period | Amount |
|---|---|
| Monthly | $10,965 |
| Semi-monthly (24 a year) | $5,482.50 |
| Biweekly (26 a year) | $5,060.77 |
| Weekly | $2,530.38 |
| Hourly | $63.26 |
Based on a full-time year of 2,080 hours. Convert any amount with the hourly to salary converter.
Nurse Practitioner salary in other metro areas nearby
| Metro area | Median salary | Workers |
|---|---|---|
| Bloomington, IL | $139,190 | 90 |
| Champaign-Urbana, IL | $137,100 | 420 |
| Chicago-Naperville-Elgin, IL-IN | $131,740 | 6,530 |
| Kansas City, MO-KS | $130,760 | 2,730 |
| Davenport-Moline-Rock Island, IA-IL | $130,400 | 390 |
| Springfield, IL | $130,200 | 350 |
| Cape Girardeau, MO-IL | $130,000 | 200 |
| Columbia, MO | $128,930 | 330 |
| Peoria, IL | $128,920 | 320 |
| Jefferson City, MO | $128,710 | 130 |
| St. Joseph, MO-KS | $128,710 | 140 |
| Kankakee, IL | $128,320 | 100 |
| Rockford, IL | $127,720 | 240 |
| Joplin, MO-KS | $126,640 | 230 |
| Springfield, MO | $125,630 | 660 |
| Paducah, KY-IL | $124,200 | 110 |
| Decatur, IL | $110,820 | 80 |
Highest-paying states for nurse practitioners
| State | Median salary |
|---|---|
| California | $168,520 |
| New Jersey | $159,310 |
| Washington | $156,100 |
| Oregon | $155,680 |
| Alaska | $155,170 |
| New York | $153,510 |
| Massachusetts | $142,440 |
| Nevada | $140,670 |
| Connecticut | $138,470 |
| New Hampshire | $137,550 |
See Nurse Practitioner pay in every state or the Missouri statewide figures.
Related jobs in St. Louis, MO-IL
| Job | Median salary | Hourly |
|---|---|---|
| Registered Nurse | $83,180 | $39.99 |
| Pharmacist | $138,530 | $66.60 |
| Physical Therapist | $100,600 | $48.37 |
| Physicians, All Other | $246,440 | $118.48 |
| Dental Hygienist | $97,650 | $46.95 |
| Occupational Therapist | $95,770 | $46.04 |
| Family Medicine Physician | $76,830 | $36.94 |
| Speech-Language Pathologist | $86,480 | $41.58 |
| Physician Assistant | $136,120 | $65.44 |
| Respiratory Therapist | $79,210 | $38.08 |
| Dentists, General | $210,430 | $101.17 |
| Veterinarian | $122,460 | $58.87 |
| Dietitians and Nutritionists | $70,360 | $33.83 |
| Nurse Anesthetist | $232,300 | $111.68 |
More: Healthcare Practitioners and Technical Occupations · all salaries in St. Louis, MO-IL
Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025 estimates, occupation code 29-1171. Wages include base pay, tips, commissions and shift pay, but not overtime, bonuses or benefits, and exclude the self-employed.
Frequently asked questions
How much does a nurse practitioner make in St. Louis, MO-IL?
The median salary for nurse practitioners in the St. Louis, MO-IL metro area is $131,580 a year, or $63.26 an hour. Pay ranges from $108,340 for the lowest-paid 10% to $164,280 for the top 10%.
How much do the highest-paid nurse practitioners make in St. Louis, MO-IL?
The top 10% of nurse practitioners in the St. Louis, MO-IL metro area earn at least $164,280 a year. The top 25% earn $154,500 or more.
What is the starting pay for nurse practitioners in St. Louis, MO-IL?
Entry-level pay (the 10th percentile) is about $108,340 a year, and a quarter of nurse practitioners earn $127,460 or less.
How many nurse practitioners work in St. Louis, MO-IL?
About 3,430 nurse practitioners are employed in the St. Louis, MO-IL metro area, not counting the self-employed.