Nurse Practitioner salary in Jefferson City, MO

Nurse Practitioners in the Jefferson City, MO metro area earn a median of $128,710 a year ($61.88 an hour), based on BLS data for 130 workers.

Median salary
$128,710
Hourly
$61.88
Average
$124,800
Top 10% earn
$153,190
Workers
130

Pay ranges from $103,470 for the lowest-paid 10% to $153,190 for the top 10%. That is 3% lower than the national median of $132,300. Pay here is 1% lower than the Missouri statewide median of $129,930. There are 1.6 nurse practitioners per 1,000 jobs here — the job is less common than nationally (location quotient 0.77). The average (mean) salary is $124,800, close to the median.

Pay range for nurse practitioners in Jefferson City, MO

$0$190,000
Pay levelYearlyHourly
10th percentile (entry level)$103,470$49.75
25th percentile$105,920$50.92
Median$128,710$61.88
75th percentile$133,920$64.39
90th percentile (top earners)$153,190$73.65
Average (mean)$124,800$60.00

Half of nurse practitioners earn more than the median and half earn less. Percentiles show the spread: 10% earn less than the 10th percentile, and 10% earn more than the 90th.

Median paycheck, before taxes

Pay periodAmount
Monthly$10,725.83
Semi-monthly (24 a year)$5,362.92
Biweekly (26 a year)$4,950.38
Weekly$2,475.19
Hourly$61.88

Based on a full-time year of 2,080 hours. Convert any amount with the hourly to salary converter.

Nurse Practitioner salary in other metro areas nearby

Metro areaMedian salaryWorkers
St. Louis, MO-IL$131,5803,430
Kansas City, MO-KS$130,7602,730
Cape Girardeau, MO-IL$130,000200
Columbia, MO$128,930330
St. Joseph, MO-KS$128,710140
Joplin, MO-KS$126,640230
Springfield, MO$125,630660

Highest-paying states for nurse practitioners

StateMedian salary
California$168,520
New Jersey$159,310
Washington$156,100
Oregon$155,680
Alaska$155,170
New York$153,510
Massachusetts$142,440
Nevada$140,670
Connecticut$138,470
New Hampshire$137,550

See Nurse Practitioner pay in every state or the Missouri statewide figures.

Related jobs in Jefferson City, MO

JobMedian salaryHourly
Registered Nurse$85,010$40.87
Pharmacist$130,190$62.59
Physical Therapist$98,070$47.15
Dental Hygienist$85,290$41.01
Dentists, General$208,630$100.30
Dietitians and Nutritionists$62,490$30.05
Occupational Therapist$95,110$45.73
Physicians, All Other$220,460$105.99
Respiratory Therapist$77,500$37.26
Speech-Language Pathologist$83,740$40.26
Veterinarian$101,230$48.67
Family Medicine Physician$224,100$107.74
Physician Assistant$135,340$65.07
Psychiatrist$282,050$135.60

More: Healthcare Practitioners and Technical Occupations · all salaries in Jefferson City, MO

Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025 estimates, occupation code 29-1171. Wages include base pay, tips, commissions and shift pay, but not overtime, bonuses or benefits, and exclude the self-employed.

Frequently asked questions

How much does a nurse practitioner make in Jefferson City, MO?

The median salary for nurse practitioners in the Jefferson City, MO metro area is $128,710 a year, or $61.88 an hour. Pay ranges from $103,470 for the lowest-paid 10% to $153,190 for the top 10%.

How much do the highest-paid nurse practitioners make in Jefferson City, MO?

The top 10% of nurse practitioners in the Jefferson City, MO metro area earn at least $153,190 a year. The top 25% earn $133,920 or more.

What is the starting pay for nurse practitioners in Jefferson City, MO?

Entry-level pay (the 10th percentile) is about $103,470 a year, and a quarter of nurse practitioners earn $105,920 or less.

How many nurse practitioners work in Jefferson City, MO?

About 130 nurse practitioners are employed in the Jefferson City, MO metro area, not counting the self-employed.