Registered Nurse salary in Missouri

Registered Nurses in Missouri earn a median of $81,780 a year ($39.32 an hour), based on BLS data for 76,310 workers.

Median salary
$81,780
Hourly
$39.32
Average
$85,900
Top 10% earn
$104,390
Workers
76,310

Pay ranges from $63,230 for the lowest-paid 10% to $104,390 for the top 10%. That is 16% lower than the national median of $97,550. Missouri ranks 40th of 51 states for registered nurses pay. There are 26 registered nurses per 1,000 jobs here — the job is 1.2× more common than nationally. The average (mean) salary is $85,900, above the median because a few high earners pull it up.

Pay range for registered nurses in Missouri

$0$150,000
Pay levelYearlyHourly
10th percentile (entry level)$63,230$30.40
25th percentile$76,050$36.56
Median$81,780$39.32
75th percentile$98,560$47.39
90th percentile (top earners)$104,390$50.19
Average (mean)$85,900$41.30

Half of registered nurses earn more than the median and half earn less. Percentiles show the spread: 10% earn less than the 10th percentile, and 10% earn more than the 90th.

Median paycheck, before taxes

Pay periodAmount
Monthly$6,815
Semi-monthly (24 a year)$3,407.50
Biweekly (26 a year)$3,145.38
Weekly$1,572.69
Hourly$39.32

Based on a full-time year of 2,080 hours. Convert any amount with the hourly to salary converter.

Registered Nurse salary in cities in Missouri

Metro areaMedian salaryWorkers
Jefferson City, MO$85,0101,910
Columbia, MO$84,3303,680
St. Louis, MO-IL$83,18035,200
Kansas City, MO-KS$83,04029,650
Cape Girardeau, MO-IL$82,6401,470
Springfield, MO$79,3706,820
St. Joseph, MO-KS$77,2401,490
Joplin, MO-KS$74,9302,670

Highest-paying states for registered nurses

StateMedian salary
California$140,270
Hawaii$136,320
Oregon$129,010
Washington$124,200
Alaska$109,480
New York$109,440
New Jersey$106,500
Massachusetts$104,550
Nevada$103,670
Connecticut$102,740

See Registered Nurse pay in every state.

Related jobs in Missouri

JobMedian salaryHourly
Nurse Practitioner$129,930$62.47
Pharmacist$137,610$66.16
Physical Therapist$99,310$47.75
Physicians, All Other$227,980$109.61
Dental Hygienist$92,750$44.59
Family Medicine Physician$171,180$82.30
Occupational Therapist$97,290$46.77
Speech-Language Pathologist$89,280$42.92
Respiratory Therapist$78,390$37.69
Dentists, General$204,960$98.54
Physician Assistant$135,130$64.96
Veterinarian$114,660$55.12
Dietitians and Nutritionists$65,450$31.47
Nurse Anesthetist$242,630$116.65

More: Healthcare Practitioners and Technical Occupations · all salaries in Missouri

Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025 estimates, occupation code 29-1141. Wages include base pay, tips, commissions and shift pay, but not overtime, bonuses or benefits, and exclude the self-employed.

Frequently asked questions

How much does a registered nurse make in Missouri?

The median salary for registered nurses in Missouri is $81,780 a year, or $39.32 an hour. Pay ranges from $63,230 for the lowest-paid 10% to $104,390 for the top 10%.

How much do the highest-paid registered nurses make in Missouri?

The top 10% of registered nurses in Missouri earn at least $104,390 a year. The top 25% earn $98,560 or more.

What is the starting pay for registered nurses in Missouri?

Entry-level pay (the 10th percentile) is about $63,230 a year, and a quarter of registered nurses earn $76,050 or less.

How many registered nurses work in Missouri?

About 76,310 registered nurses are employed in Missouri, not counting the self-employed.