Registered Nurse salary in Cape Girardeau, MO-IL

Registered Nurses in the Cape Girardeau, MO-IL metro area earn a median of $82,640 a year ($39.73 an hour), based on BLS data for 1,470 workers.

Median salary
$82,640
Hourly
$39.73
Average
$86,160
Top 10% earn
$104,830
Workers
1,470

Pay ranges from $62,620 for the lowest-paid 10% to $104,830 for the top 10%. That is 15% lower than the national median of $97,550. Pay here is 1% higher than the Missouri statewide median of $81,780. There are 33 registered nurses per 1,000 jobs here — the job is 1.5× more common than nationally. The average (mean) salary is $86,160, above the median because a few high earners pull it up.

Pay range for registered nurses in Cape Girardeau, MO-IL

$0$150,000
Pay levelYearlyHourly
10th percentile (entry level)$62,620$30.11
25th percentile$67,790$32.59
Median$82,640$39.73
75th percentile$93,330$44.87
90th percentile (top earners)$104,830$50.40
Average (mean)$86,160$41.42

Half of registered nurses earn more than the median and half earn less. Percentiles show the spread: 10% earn less than the 10th percentile, and 10% earn more than the 90th.

Median paycheck, before taxes

Pay periodAmount
Monthly$6,886.67
Semi-monthly (24 a year)$3,443.33
Biweekly (26 a year)$3,178.46
Weekly$1,589.23
Hourly$39.73

Based on a full-time year of 2,080 hours. Convert any amount with the hourly to salary converter.

Registered Nurse salary in other metro areas nearby

Metro areaMedian salaryWorkers
Chicago-Naperville-Elgin, IL-IN$100,490100,240
Champaign-Urbana, IL$90,2303,520
Decatur, IL$87,170790
Kankakee, IL$86,2201,390
Jefferson City, MO$85,0101,910
Columbia, MO$84,3303,680
Springfield, IL$84,2204,110
St. Louis, MO-IL$83,18035,200
Kansas City, MO-KS$83,04029,650
Peoria, IL$81,0105,460
Rockford, IL$80,9304,620
Bloomington, IL$79,9701,990
Paducah, KY-IL$79,9201,720
Springfield, MO$79,3706,820
St. Joseph, MO-KS$77,2401,490
Davenport-Moline-Rock Island, IA-IL$77,1503,520
Joplin, MO-KS$74,9302,670

Highest-paying states for registered nurses

StateMedian salary
California$140,270
Hawaii$136,320
Oregon$129,010
Washington$124,200
Alaska$109,480
New York$109,440
New Jersey$106,500
Massachusetts$104,550
Nevada$103,670
Connecticut$102,740

See Registered Nurse pay in every state or the Missouri statewide figures.

Related jobs in Cape Girardeau, MO-IL

More: Healthcare Practitioners and Technical Occupations · all salaries in Cape Girardeau, MO-IL

Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025 estimates, occupation code 29-1141. Wages include base pay, tips, commissions and shift pay, but not overtime, bonuses or benefits, and exclude the self-employed.

Frequently asked questions

How much does a registered nurse make in Cape Girardeau, MO-IL?

The median salary for registered nurses in the Cape Girardeau, MO-IL metro area is $82,640 a year, or $39.73 an hour. Pay ranges from $62,620 for the lowest-paid 10% to $104,830 for the top 10%.

How much do the highest-paid registered nurses make in Cape Girardeau, MO-IL?

The top 10% of registered nurses in the Cape Girardeau, MO-IL metro area earn at least $104,830 a year. The top 25% earn $93,330 or more.

What is the starting pay for registered nurses in Cape Girardeau, MO-IL?

Entry-level pay (the 10th percentile) is about $62,620 a year, and a quarter of registered nurses earn $67,790 or less.

How many registered nurses work in Cape Girardeau, MO-IL?

About 1,470 registered nurses are employed in the Cape Girardeau, MO-IL metro area, not counting the self-employed.