Nurse Practitioner salary in Spartanburg, SC
Nurse Practitioners in the Spartanburg, SC metro area earn a median of $121,120 a year ($58.23 an hour), based on BLS data for 260 workers.
Pay ranges from $103,270 for the lowest-paid 10% to $156,840 for the top 10%. That is 8% lower than the national median of $132,300. Pay here is 2% lower than the South Carolina statewide median of $123,290. There are 1.6 nurse practitioners per 1,000 jobs here — the job is less common than nationally (location quotient 0.77). The average (mean) salary is $128,140, above the median because a few high earners pull it up.
Pay range for nurse practitioners in Spartanburg, SC
| Pay level | Yearly | Hourly |
|---|---|---|
| 10th percentile (entry level) | $103,270 | $49.65 |
| 25th percentile | $109,350 | $52.57 |
| Median | $121,120 | $58.23 |
| 75th percentile | $132,190 | $63.56 |
| 90th percentile (top earners) | $156,840 | $75.40 |
| Average (mean) | $128,140 | $61.61 |
Half of nurse practitioners earn more than the median and half earn less. Percentiles show the spread: 10% earn less than the 10th percentile, and 10% earn more than the 90th.
Median paycheck, before taxes
| Pay period | Amount |
|---|---|
| Monthly | $10,093.33 |
| Semi-monthly (24 a year) | $5,046.67 |
| Biweekly (26 a year) | $4,658.46 |
| Weekly | $2,329.23 |
| Hourly | $58.23 |
Based on a full-time year of 2,080 hours. Convert any amount with the hourly to salary converter.
Nurse Practitioner salary in other metro areas nearby
| Metro area | Median salary | Workers |
|---|---|---|
| Charlotte-Concord-Gastonia, NC-SC | $130,310 | 1,970 |
| Charleston-North Charleston, SC | $127,780 | 1,050 |
| Florence, SC | $121,930 | 270 |
| Myrtle Beach-Conway-North Myrtle Beach, SC | $121,390 | 260 |
| Augusta-Richmond County, GA-SC | $120,270 | 500 |
| Greenville-Anderson-Greer, SC | $119,280 | 1,120 |
| Hilton Head Island-Bluffton-Port Royal, SC | $119,130 | 260 |
| Columbia, SC | $118,470 | 920 |
| Sumter, SC | $112,080 | 80 |
Highest-paying states for nurse practitioners
| State | Median salary |
|---|---|
| California | $168,520 |
| New Jersey | $159,310 |
| Washington | $156,100 |
| Oregon | $155,680 |
| Alaska | $155,170 |
| New York | $153,510 |
| Massachusetts | $142,440 |
| Nevada | $140,670 |
| Connecticut | $138,470 |
| New Hampshire | $137,550 |
See Nurse Practitioner pay in every state or the South Carolina statewide figures.
Related jobs in Spartanburg, SC
| Job | Median salary | Hourly |
|---|---|---|
| Registered Nurse | $82,360 | $39.60 |
| Pharmacist | $153,610 | $73.85 |
| Physical Therapist | $111,860 | $53.78 |
| Physicians, All Other | $131,460 | $63.20 |
| Respiratory Therapist | $67,700 | $32.55 |
| Occupational Therapist | $111,540 | $53.63 |
| Speech-Language Pathologist | $96,330 | $46.31 |
| Dental Hygienist | $83,780 | $40.28 |
| Dentists, General | $140,360 | $67.48 |
| Physician Assistant | $121,990 | $58.65 |
| Dietitians and Nutritionists | $72,790 | $35.00 |
| Family Medicine Physician | $241,070 | $115.90 |
| General Internal Medicine Physician | $284,250 | $136.66 |
| Veterinarian | $121,420 | $58.37 |
More: Healthcare Practitioners and Technical Occupations · all salaries in Spartanburg, SC
Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025 estimates, occupation code 29-1171. Wages include base pay, tips, commissions and shift pay, but not overtime, bonuses or benefits, and exclude the self-employed.
Frequently asked questions
How much does a nurse practitioner make in Spartanburg, SC?
The median salary for nurse practitioners in the Spartanburg, SC metro area is $121,120 a year, or $58.23 an hour. Pay ranges from $103,270 for the lowest-paid 10% to $156,840 for the top 10%.
How much do the highest-paid nurse practitioners make in Spartanburg, SC?
The top 10% of nurse practitioners in the Spartanburg, SC metro area earn at least $156,840 a year. The top 25% earn $132,190 or more.
What is the starting pay for nurse practitioners in Spartanburg, SC?
Entry-level pay (the 10th percentile) is about $103,270 a year, and a quarter of nurse practitioners earn $109,350 or less.
How many nurse practitioners work in Spartanburg, SC?
About 260 nurse practitioners are employed in the Spartanburg, SC metro area, not counting the self-employed.