Nurse Practitioner salary in Charleston-North Charleston, SC

Nurse Practitioners in the Charleston-North Charleston, SC metro area earn a median of $127,780 a year ($61.43 an hour), based on BLS data for 1,050 workers.

Median salary
$127,780
Hourly
$61.43
Average
$126,750
Top 10% earn
$157,170
Workers
1,050

Pay ranges from $103,200 for the lowest-paid 10% to $157,170 for the top 10%. That is 3% lower than the national median of $132,300. Pay here is 4% higher than the South Carolina statewide median of $123,290. There are 2.7 nurse practitioners per 1,000 jobs here — the job is 1.3× more common than nationally. The average (mean) salary is $126,750, close to the median.

Pay range for nurse practitioners in Charleston-North Charleston, SC

$0$190,000
Pay levelYearlyHourly
10th percentile (entry level)$103,200$49.61
25th percentile$117,480$56.48
Median$127,780$61.43
75th percentile$133,050$63.96
90th percentile (top earners)$157,170$75.56
Average (mean)$126,750$60.94

Half of nurse practitioners earn more than the median and half earn less. Percentiles show the spread: 10% earn less than the 10th percentile, and 10% earn more than the 90th.

Median paycheck, before taxes

Pay periodAmount
Monthly$10,648.33
Semi-monthly (24 a year)$5,324.17
Biweekly (26 a year)$4,914.62
Weekly$2,457.31
Hourly$61.43

Based on a full-time year of 2,080 hours. Convert any amount with the hourly to salary converter.

Buying a home? On a $127,780 salary, see how much house you can afford in South Carolina at today's mortgage rates, or work out a payment with the mortgage calculator.

Nurse Practitioner salary in other metro areas nearby

Highest-paying states for nurse practitioners

StateMedian salary
California$168,520
New Jersey$159,310
Washington$156,100
Oregon$155,680
Alaska$155,170
New York$153,510
Massachusetts$142,440
Nevada$140,670
Connecticut$138,470
New Hampshire$137,550

See Nurse Practitioner pay in every state or the South Carolina statewide figures.

Related jobs in Charleston-North Charleston, SC

JobMedian salaryHourly
Registered Nurse$92,800$44.62
Physicians, All Other$163,900$78.80
Pharmacist$145,950$70.17
Physical Therapist$101,550$48.82
Physician Assistant$128,920$61.98
Dental Hygienist$94,570$45.46
Dentists, General$121,090$58.22
Respiratory Therapist$79,410$38.18
Speech-Language Pathologist$98,790$47.50
Veterinarian$122,130$58.72
Occupational Therapist$98,530$47.37
Family Medicine Physician$255,650$122.91
Dietitians and Nutritionists$76,550$36.80
Chiropractor$76,750$36.90

More: Healthcare Practitioners and Technical Occupations · all salaries in Charleston-North Charleston, SC

Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025 estimates, occupation code 29-1171. Wages include base pay, tips, commissions and shift pay, but not overtime, bonuses or benefits, and exclude the self-employed.

Frequently asked questions

How much does a nurse practitioner make in Charleston-North Charleston, SC?

The median salary for nurse practitioners in the Charleston-North Charleston, SC metro area is $127,780 a year, or $61.43 an hour. Pay ranges from $103,200 for the lowest-paid 10% to $157,170 for the top 10%.

How much do the highest-paid nurse practitioners make in Charleston-North Charleston, SC?

The top 10% of nurse practitioners in the Charleston-North Charleston, SC metro area earn at least $157,170 a year. The top 25% earn $133,050 or more.

What is the starting pay for nurse practitioners in Charleston-North Charleston, SC?

Entry-level pay (the 10th percentile) is about $103,200 a year, and a quarter of nurse practitioners earn $117,480 or less.

How many nurse practitioners work in Charleston-North Charleston, SC?

About 1,050 nurse practitioners are employed in the Charleston-North Charleston, SC metro area, not counting the self-employed.