Physician Assistant salary in Spartanburg, SC
Physician Assistants in the Spartanburg, SC metro area earn a median of $121,990 a year ($58.65 an hour), based on BLS data for 80 workers.
Pay ranges from $99,720 for the lowest-paid 10% to $166,320 for the top 10%. That is 10% lower than the national median of $135,880. Pay here is about the same as the South Carolina statewide median of $122,490. There are 0.50 physician assistants per 1,000 jobs here — the job is less common than nationally (location quotient 0.48). The average (mean) salary is $127,780, above the median because a few high earners pull it up.
Pay range for physician assistants in Spartanburg, SC
| Pay level | Yearly | Hourly |
|---|---|---|
| 10th percentile (entry level) | $99,720 | $47.94 |
| 25th percentile | $111,680 | $53.69 |
| Median | $121,990 | $58.65 |
| 75th percentile | $132,320 | $63.62 |
| 90th percentile (top earners) | $166,320 | $79.96 |
| Average (mean) | $127,780 | $61.43 |
Half of physician assistants earn more than the median and half earn less. Percentiles show the spread: 10% earn less than the 10th percentile, and 10% earn more than the 90th.
Median paycheck, before taxes
| Pay period | Amount |
|---|---|
| Monthly | $10,165.83 |
| Semi-monthly (24 a year) | $5,082.92 |
| Biweekly (26 a year) | $4,691.92 |
| Weekly | $2,345.96 |
| Hourly | $58.65 |
Based on a full-time year of 2,080 hours. Convert any amount with the hourly to salary converter.
Buying a home? On a $121,990 salary, see how much house you can afford in South Carolina at today's mortgage rates, or work out a payment with the mortgage calculator.
Physician Assistant salary in other metro areas nearby
| Metro area | Median salary | Workers |
|---|---|---|
| Charlotte-Concord-Gastonia, NC-SC | $133,140 | 1,680 |
| Charleston-North Charleston, SC | $128,920 | 620 |
| Myrtle Beach-Conway-North Myrtle Beach, SC | $125,700 | 140 |
| Hilton Head Island-Bluffton-Port Royal, SC | $125,350 | 80 |
| Greenville-Anderson-Greer, SC | $123,310 | 440 |
| Florence, SC | $120,290 | 90 |
| Augusta-Richmond County, GA-SC | $117,240 | 350 |
| Columbia, SC | $115,840 | 400 |
Highest-paying states for physician assistants
| State | Median salary |
|---|---|
| New Jersey | $165,690 |
| California | $165,650 |
| Washington | $164,360 |
| Hawaii | $164,050 |
| New York | $160,880 |
| Oregon | $155,780 |
| New Hampshire | $150,960 |
| Alaska | $150,700 |
| Vermont | $150,490 |
| Massachusetts | $142,410 |
See Physician Assistant pay in every state or the South Carolina statewide figures.
Related jobs in Spartanburg, SC
| Job | Median salary | Hourly |
|---|---|---|
| Registered Nurse | $82,360 | $39.60 |
| Pharmacist | $153,610 | $73.85 |
| Physical Therapist | $111,860 | $53.78 |
| Nurse Practitioner | $121,120 | $58.23 |
| Physicians, All Other | $131,460 | $63.20 |
| Respiratory Therapist | $67,700 | $32.55 |
| Occupational Therapist | $111,540 | $53.63 |
| Speech-Language Pathologist | $96,330 | $46.31 |
| Dental Hygienist | $83,780 | $40.28 |
| Dentists, General | $140,360 | $67.48 |
| Dietitians and Nutritionists | $72,790 | $35.00 |
| Family Medicine Physician | $241,070 | $115.90 |
| General Internal Medicine Physician | $284,250 | $136.66 |
| Veterinarian | $121,420 | $58.37 |
More: Healthcare Practitioners and Technical Occupations · all salaries in Spartanburg, SC
Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025 estimates, occupation code 29-1071. Wages include base pay, tips, commissions and shift pay, but not overtime, bonuses or benefits, and exclude the self-employed.
Frequently asked questions
How much does a physician assistant make in Spartanburg, SC?
The median salary for physician assistants in the Spartanburg, SC metro area is $121,990 a year, or $58.65 an hour. Pay ranges from $99,720 for the lowest-paid 10% to $166,320 for the top 10%.
How much do the highest-paid physician assistants make in Spartanburg, SC?
The top 10% of physician assistants in the Spartanburg, SC metro area earn at least $166,320 a year. The top 25% earn $132,320 or more.
What is the starting pay for physician assistants in Spartanburg, SC?
Entry-level pay (the 10th percentile) is about $99,720 a year, and a quarter of physician assistants earn $111,680 or less.
How many physician assistants work in Spartanburg, SC?
About 80 physician assistants are employed in the Spartanburg, SC metro area, not counting the self-employed.