Registered Nurse salary in Florence, SC
Registered Nurses in the Florence, SC metro area earn a median of $81,170 a year ($39.02 an hour), based on BLS data for 3,120 workers.
Pay ranges from $65,710 for the lowest-paid 10% to $174,900 for the top 10%. That is 17% lower than the national median of $97,550. Pay here is 1% lower than the South Carolina statewide median of $82,360. There are 35 registered nurses per 1,000 jobs here — the job is 1.6× more common than nationally. The average (mean) salary is $100,700, above the median because a few high earners pull it up.
Pay range for registered nurses in Florence, SC
| Pay level | Yearly | Hourly |
|---|---|---|
| 10th percentile (entry level) | $65,710 | $31.59 |
| 25th percentile | $66,860 | $32.14 |
| Median | $81,170 | $39.02 |
| 75th percentile | $125,840 | $60.50 |
| 90th percentile (top earners) | $174,900 | $84.09 |
| Average (mean) | $100,700 | $48.41 |
Half of registered nurses earn more than the median and half earn less. Percentiles show the spread: 10% earn less than the 10th percentile, and 10% earn more than the 90th.
Median paycheck, before taxes
| Pay period | Amount |
|---|---|
| Monthly | $6,764.17 |
| Semi-monthly (24 a year) | $3,382.08 |
| Biweekly (26 a year) | $3,121.92 |
| Weekly | $1,560.96 |
| Hourly | $39.02 |
Based on a full-time year of 2,080 hours. Convert any amount with the hourly to salary converter.
Registered Nurse salary in other metro areas nearby
| Metro area | Median salary | Workers |
|---|---|---|
| Charleston-North Charleston, SC | $92,800 | 9,760 |
| Charlotte-Concord-Gastonia, NC-SC | $90,620 | 27,010 |
| Augusta-Richmond County, GA-SC | $87,760 | 6,880 |
| Sumter, SC | $86,260 | 670 |
| Spartanburg, SC | $82,360 | 4,440 |
| Columbia, SC | $81,920 | 9,400 |
| Greenville-Anderson-Greer, SC | $81,400 | 9,730 |
| Hilton Head Island-Bluffton-Port Royal, SC | $81,400 | 1,410 |
| Myrtle Beach-Conway-North Myrtle Beach, SC | $80,640 | 3,150 |
Highest-paying states for registered nurses
| State | Median salary |
|---|---|
| California | $140,270 |
| Hawaii | $136,320 |
| Oregon | $129,010 |
| Washington | $124,200 |
| Alaska | $109,480 |
| New York | $109,440 |
| New Jersey | $106,500 |
| Massachusetts | $104,550 |
| Nevada | $103,670 |
| Connecticut | $102,740 |
See Registered Nurse pay in every state or the South Carolina statewide figures.
Related jobs in Florence, SC
| Job | Median salary | Hourly |
|---|---|---|
| Physicians, All Other | $282,920 | $136.02 |
| Pharmacist | $155,020 | $74.53 |
| Nurse Practitioner | $121,930 | $58.62 |
| Dental Hygienist | $81,200 | $39.04 |
| Physical Therapist | $108,160 | $52.00 |
| Respiratory Therapist | $78,550 | $37.77 |
| Dietitians and Nutritionists | $65,080 | $31.29 |
| Physician Assistant | $120,290 | $57.83 |
| Speech-Language Pathologist | $96,390 | $46.34 |
| Occupational Therapist | $101,510 | $48.80 |
| Dentists, General | $137,260 | $65.99 |
| General Internal Medicine Physician | $348,250 | $167.43 |
| Family Medicine Physician | $257,170 | $123.64 |
| Licensed Practical and Licensed Vocational Nurses | $59,700 | $28.70 |
More: Healthcare Practitioners and Technical Occupations · all salaries in Florence, SC
Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025 estimates, occupation code 29-1141. Wages include base pay, tips, commissions and shift pay, but not overtime, bonuses or benefits, and exclude the self-employed.
Frequently asked questions
How much does a registered nurse make in Florence, SC?
The median salary for registered nurses in the Florence, SC metro area is $81,170 a year, or $39.02 an hour. Pay ranges from $65,710 for the lowest-paid 10% to $174,900 for the top 10%.
How much do the highest-paid registered nurses make in Florence, SC?
The top 10% of registered nurses in the Florence, SC metro area earn at least $174,900 a year. The top 25% earn $125,840 or more.
What is the starting pay for registered nurses in Florence, SC?
Entry-level pay (the 10th percentile) is about $65,710 a year, and a quarter of registered nurses earn $66,860 or less.
How many registered nurses work in Florence, SC?
About 3,120 registered nurses are employed in the Florence, SC metro area, not counting the self-employed.