Registered Nurse salary in Columbia, SC

Registered Nurses in the Columbia, SC metro area earn a median of $81,920 a year ($39.39 an hour), based on BLS data for 9,400 workers.

Median salary
$81,920
Hourly
$39.39
Average
$88,030
Top 10% earn
$108,210
Workers
9,400

Pay ranges from $68,460 for the lowest-paid 10% to $108,210 for the top 10%. That is 16% lower than the national median of $97,550. Pay here is 1% lower than the South Carolina statewide median of $82,360. There are 24 registered nurses per 1,000 jobs here — close to the national average. The average (mean) salary is $88,030, above the median because a few high earners pull it up.

Pay range for registered nurses in Columbia, SC

$0$150,000
Pay levelYearlyHourly
10th percentile (entry level)$68,460$32.91
25th percentile$75,940$36.51
Median$81,920$39.39
75th percentile$96,190$46.24
90th percentile (top earners)$108,210$52.03
Average (mean)$88,030$42.32

Half of registered nurses earn more than the median and half earn less. Percentiles show the spread: 10% earn less than the 10th percentile, and 10% earn more than the 90th.

Median paycheck, before taxes

Pay periodAmount
Monthly$6,826.67
Semi-monthly (24 a year)$3,413.33
Biweekly (26 a year)$3,150.77
Weekly$1,575.38
Hourly$39.39

Based on a full-time year of 2,080 hours. Convert any amount with the hourly to salary converter.

Registered Nurse salary in other metro areas nearby

Highest-paying states for registered nurses

StateMedian salary
California$140,270
Hawaii$136,320
Oregon$129,010
Washington$124,200
Alaska$109,480
New York$109,440
New Jersey$106,500
Massachusetts$104,550
Nevada$103,670
Connecticut$102,740

See Registered Nurse pay in every state or the South Carolina statewide figures.

Related jobs in Columbia, SC

JobMedian salaryHourly
Pharmacist$133,850$64.35
Physicians, All Other$374,300$179.95
Nurse Practitioner$118,470$56.96
Physical Therapist$99,840$48.00
Dental Hygienist$82,370$39.60
Dentists, General$228,820$110.01
Physician Assistant$115,840$55.69
Speech-Language Pathologist$87,820$42.22
Respiratory Therapist$79,780$38.36
Occupational Therapist$102,650$49.35
Nurse Anesthetist$271,350$130.46
Veterinarian$129,960$62.48
Dietitians and Nutritionists$68,080$32.73
Chiropractor$74,090$35.62

More: Healthcare Practitioners and Technical Occupations · all salaries in Columbia, SC

Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025 estimates, occupation code 29-1141. Wages include base pay, tips, commissions and shift pay, but not overtime, bonuses or benefits, and exclude the self-employed.

Frequently asked questions

How much does a registered nurse make in Columbia, SC?

The median salary for registered nurses in the Columbia, SC metro area is $81,920 a year, or $39.39 an hour. Pay ranges from $68,460 for the lowest-paid 10% to $108,210 for the top 10%.

How much do the highest-paid registered nurses make in Columbia, SC?

The top 10% of registered nurses in the Columbia, SC metro area earn at least $108,210 a year. The top 25% earn $96,190 or more.

What is the starting pay for registered nurses in Columbia, SC?

Entry-level pay (the 10th percentile) is about $68,460 a year, and a quarter of registered nurses earn $75,940 or less.

How many registered nurses work in Columbia, SC?

About 9,400 registered nurses are employed in the Columbia, SC metro area, not counting the self-employed.