Nurse Practitioner salary in Knoxville, TN

Nurse Practitioners in the Knoxville, TN metro area earn a median of $109,740 a year ($52.76 an hour), based on BLS data for 1,630 workers.

Median salary
$109,740
Hourly
$52.76
Average
$112,460
Top 10% earn
$135,170
Workers
1,630

Pay ranges from $85,210 for the lowest-paid 10% to $135,170 for the top 10%. That is 17% lower than the national median of $132,300. Pay here is 7% lower than the Tennessee statewide median of $117,590. There are 3.8 nurse practitioners per 1,000 jobs here — the job is 1.9× more common than nationally. The average (mean) salary is $112,460, above the median because a few high earners pull it up.

Pay range for nurse practitioners in Knoxville, TN

$0$190,000
Pay levelYearlyHourly
10th percentile (entry level)$85,210$40.97
25th percentile$101,220$48.66
Median$109,740$52.76
75th percentile$128,620$61.84
90th percentile (top earners)$135,170$64.99
Average (mean)$112,460$54.07

Half of nurse practitioners earn more than the median and half earn less. Percentiles show the spread: 10% earn less than the 10th percentile, and 10% earn more than the 90th.

Median paycheck, before taxes

Pay periodAmount
Monthly$9,145
Semi-monthly (24 a year)$4,572.50
Biweekly (26 a year)$4,220.77
Weekly$2,110.38
Hourly$52.76

Based on a full-time year of 2,080 hours. Convert any amount with the hourly to salary converter.

Nurse Practitioner salary in other metro areas nearby

Metro areaMedian salaryWorkers
Memphis, TN-MS-AR$124,6001,800
Nashville-Davidson--Murfreesboro--Franklin, TN$122,3204,540
Kingsport-Bristol, TN-VA$118,470480
Chattanooga, TN-GA$116,4801,000
Clarksville, TN-KY$115,160300
Jackson, TN$108,260410
Cleveland, TN$107,360170
Morristown, TN$105,560120
Johnson City, TN$102,430380

Highest-paying states for nurse practitioners

StateMedian salary
California$168,520
New Jersey$159,310
Washington$156,100
Oregon$155,680
Alaska$155,170
New York$153,510
Massachusetts$142,440
Nevada$140,670
Connecticut$138,470
New Hampshire$137,550

See Nurse Practitioner pay in every state or the Tennessee statewide figures.

Related jobs in Knoxville, TN

JobMedian salaryHourly
Registered Nurse$77,240$37.13
Pharmacist$132,460$63.68
Physicians, All Other$276,370$132.87
Dental Hygienist$84,640$40.69
Family Medicine Physician$460,080$221.19
Physical Therapist$96,110$46.21
Respiratory Therapist$64,800$31.15
Speech-Language Pathologist$78,060$37.53
Occupational Therapist$94,490$45.43
Veterinarian$121,160$58.25
Physician Assistant$107,980$51.91
Dentists, General$157,900$75.92
Nurse Anesthetist$213,900$102.84
Dietitians and Nutritionists$66,330$31.89

More: Healthcare Practitioners and Technical Occupations · all salaries in Knoxville, TN

Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025 estimates, occupation code 29-1171. Wages include base pay, tips, commissions and shift pay, but not overtime, bonuses or benefits, and exclude the self-employed.

Frequently asked questions

How much does a nurse practitioner make in Knoxville, TN?

The median salary for nurse practitioners in the Knoxville, TN metro area is $109,740 a year, or $52.76 an hour. Pay ranges from $85,210 for the lowest-paid 10% to $135,170 for the top 10%.

How much do the highest-paid nurse practitioners make in Knoxville, TN?

The top 10% of nurse practitioners in the Knoxville, TN metro area earn at least $135,170 a year. The top 25% earn $128,620 or more.

What is the starting pay for nurse practitioners in Knoxville, TN?

Entry-level pay (the 10th percentile) is about $85,210 a year, and a quarter of nurse practitioners earn $101,220 or less.

How many nurse practitioners work in Knoxville, TN?

About 1,630 nurse practitioners are employed in the Knoxville, TN metro area, not counting the self-employed.