Medical Assistant salary in Sioux Falls, SD-MN

Medical Assistants in the Sioux Falls, SD-MN metro area earn a median of $43,760 a year ($21.04 an hour), based on BLS data for 620 workers.

Median salary
$43,760
Hourly
$21.04
Average
$43,390
Top 10% earn
$49,540
Workers
620

Pay ranges from $36,700 for the lowest-paid 10% to $49,540 for the top 10%. That is 4% lower than the national median of $45,690. Pay here is 5% higher than the South Dakota statewide median of $41,870. There are 3.5 medical assistants per 1,000 jobs here — the job is less common than nationally (location quotient 0.66). The average (mean) salary is $43,390, close to the median.

Pay range for medical assistants in Sioux Falls, SD-MN

$0$70,000
Pay levelYearlyHourly
10th percentile (entry level)$36,700$17.64
25th percentile$38,380$18.45
Median$43,760$21.04
75th percentile$46,700$22.45
90th percentile (top earners)$49,540$23.82
Average (mean)$43,390$20.86

Half of medical assistants earn more than the median and half earn less. Percentiles show the spread: 10% earn less than the 10th percentile, and 10% earn more than the 90th.

Median paycheck, before taxes

Pay periodAmount
Monthly$3,646.67
Semi-monthly (24 a year)$1,823.33
Biweekly (26 a year)$1,683.08
Weekly$841.54
Hourly$21.04

Based on a full-time year of 2,080 hours. Convert any amount with the hourly to salary converter.

Medical Assistant salary in other metro areas nearby

Metro areaMedian salaryWorkers
Minneapolis-St. Paul-Bloomington, MN-WI$52,5707,390
Rochester, MN$49,830440
Mankato, MN$48,530200
Duluth, MN-WI$47,990750
La Crosse-Onalaska, WI-MN$47,960570
St. Cloud, MN$47,750330
Fargo, ND-MN$47,280290
Sioux City, IA-NE-SD$45,650280
Grand Forks, ND-MN$44,56080
Rapid City, SD$40,690240

Highest-paying states for medical assistants

StateMedian salary
Washington$59,290
Alaska$52,560
District of Columbia$51,050
Minnesota$50,480
Oregon$50,410
California$49,660
Massachusetts$49,460
Wisconsin$48,680
Hawaii$48,410
Colorado$48,400

See Medical Assistant pay in every state or the South Dakota statewide figures.

Related jobs in Sioux Falls, SD-MN

More: Healthcare Support Occupations · all salaries in Sioux Falls, SD-MN

Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025 estimates, occupation code 31-9092. Wages include base pay, tips, commissions and shift pay, but not overtime, bonuses or benefits, and exclude the self-employed.

Frequently asked questions

How much does a medical assistant make in Sioux Falls, SD-MN?

The median salary for medical assistants in the Sioux Falls, SD-MN metro area is $43,760 a year, or $21.04 an hour. Pay ranges from $36,700 for the lowest-paid 10% to $49,540 for the top 10%.

How much do the highest-paid medical assistants make in Sioux Falls, SD-MN?

The top 10% of medical assistants in the Sioux Falls, SD-MN metro area earn at least $49,540 a year. The top 25% earn $46,700 or more.

What is the starting pay for medical assistants in Sioux Falls, SD-MN?

Entry-level pay (the 10th percentile) is about $36,700 a year, and a quarter of medical assistants earn $38,380 or less.

How many medical assistants work in Sioux Falls, SD-MN?

About 620 medical assistants are employed in the Sioux Falls, SD-MN metro area, not counting the self-employed.